Update on precursor and early lesions of hepatocellular carcinomas.

  title={Update on precursor and early lesions of hepatocellular carcinomas.},
  author={Young Nyun Park},
  journal={Archives of pathology & laboratory medicine},
  volume={135 6},
CONTEXT There is increasing evidence to support a multistep model of the process of human hepatocarcinogenesis. Precursor lesions are characterized by the appearance of dysplastic lesions in the form of microscopic dysplastic foci and macroscopic dysplastic nodules. There are 2 types of small hepatocellular carcinoma (HCC) (≤2 cm in diameter): (1) early HCC with an indistinct margin and (2) progressed HCC with a distinct margin. Pathologic diagnostic criteria for early HCC have recently been… CONTINUE READING
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