Update on intensive motor training in spinocerebellar ataxia: time to move a step forward?

@article{Lanza2019UpdateOI,
  title={Update on intensive motor training in spinocerebellar ataxia: time to move a step forward?},
  author={Giuseppe Lanza and Jacopo Antonino Casabona and Maria Bellomo and Mariagiovanna Cantone and Francesco Fisicaro and Rita Bella and Giovanni Pennisi and Placido Bramanti and Manuela Pennisi and Alessia Bramanti},
  journal={The Journal of International Medical Research},
  year={2019},
  volume={48}
}
Some evidence suggests that high-intensity motor training slows down the severity of spinocerebellar ataxia. However, whether all patients might benefit from these activities, and by which activity, and the underlying mechanisms remain unclear. We provide an update on the effect and limitations of different training programmes in patients with spinocerebellar ataxias. Overall, data converge of the finding that intensive training is still based either on conventional rehabilitation protocols or… 
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19 Citations
Highly Influential Citations
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19 Citations

Rehabilitation for Spinocerebellar Ataxia
TLDR
Several lines of evidence suggest that high-intensity individualized physical rehabilitation programs, especially for gait and balance training, improve motor function and assistive robotic systems may improve gait stability.
International Classification of Functioning, Health and Disability (ICF) Conceptual Approach towards Spinocerebellar Ataxia
TLDR
It could be seen that rehabilitation intervention remains to be a cornerstone in current ataxia therapy, with goals of achieving exercise gains while alleviating the natural functional decline of the disease.
Home Aerobic Training for Cerebellar Degenerative Diseases: a Randomized Controlled Trial
Balance training has shown some benefits in cerebellar ataxia whereas the effects of aerobic training are relatively unknown. To determine whether a phase III trial comparing home aerobic to balance…
Balance and coordination training for patients with genetic degenerative ataxia: a systematic review
TLDR
Balance and coordination training, especially the conventional physical/occupational therapy, is able to improve the balance and coordinative function of patients with genetic degenerative ataxia, but more high-quality studies are needed to formulate recommendations for clinical practice.
Upper Body Physical Rehabilitation for Children with Ataxia through IMU-Based Exergame
TLDR
The presented exergame enhanced the participants’ hand dexterity, however, there is a need for exergames capable of maintaining a high level of players’ motivation in playing.
Impact of Nutrition in Spinocerebellar Ataxia
This chapter explores the link between the health outcomes of spinocerebellar ataxia and diet and nutrition as well as overall quality of life and well-being that is achieved as a result of…
Rehabilitation in patients with cerebellar ataxias.
TLDR
The current treatment of patients with cerebellar ataxias, especially neurodegenerative forms, genetic or not, should include these different forms of rehabilitation, with the main objective of improving the quality of life of patients.
Environmental Enrichment Enhances Cerebellar Compensation and Develops Cerebellar Reserve
  • F. Gelfo, L. Petrosini
  • Biology, Psychology
    International journal of environmental research and public health
  • 2022
TLDR
Evidence supports the role of EE in enhancing cerebellar compensation and developing cerebellars reserve by considering the studies on healthy subjects and on animals exposed to EE both before and after damage involving Cerebellar functionality.
Is Anodal Transcranial Direct Current Stimulation an Effective Ergogenic Technology in Lower Extremity Sensorimotor Control for Healthy Population? A Narrative Review
Anodal transcranial direct current stimulation (a-tDCS) aims to hone motor skills and improve the quality of life. However, the non-repeatability of experimental results and the inconsistency of…
Late-onset oro-facial dyskinesia in Spinocerebellar Ataxia type 2: a case report
TLDR
The case of late-onset oro-facial dyskinesia in an elderly patient with a genetic diagnosis of Spinocerebellar Ataxia type 2 (SCA2) is reported, and ataxin-2 ( ATXN2 ) gene analysis revealed a 36 cytosine-adenine-guanine (CAG) repeat expansion, confirming the diagnosis of SCA2.
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