Update on deep brain stimulation in Parkinson’s disease

@inproceedings{MartinezRamirez2015UpdateOD,
  title={Update on deep brain stimulation in Parkinson’s disease},
  author={Daniel Martinez-Ramirez and Wei Hu and Alberto R. Bona and Michael S. Okun and Aparna Wagle Shukla},
  booktitle={Translational Neurodegeneration},
  year={2015}
}
Deep brain stimulation (DBS) is considered a safe and well tolerated surgical procedure to alleviate Parkinson’s disease (PD) and other movement disorders symptoms along with some psychiatric conditions. Over the last few decades DBS has been shown to provide remarkable therapeutic effect on carefully selected patients. Although its precise mechanism of action is still unknown, DBS improves motor functions and therefore quality of life. To date, two main targets have emerged in PD patients: the… CONTINUE READING

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Deep brain stimulation ( DBS ) is considered a safe and well tolerated surgical procedure to alleviate Parkinson ’s disease ( PD ) and other movement disorders symptoms along with some psychiatric conditions .
Deep brain stimulation ( DBS ) is considered a safe and well tolerated surgical procedure to alleviate Parkinson ’s disease ( PD ) and other movement disorders symptoms along with some psychiatric conditions .
Deep brain stimulation ( DBS ) is considered a safe and well tolerated surgical procedure to alleviate Parkinson ’s disease ( PD ) and other movement disorders symptoms along with some psychiatric conditions .
The main indications for PD DBS have traditionally been motor fluctuations , debilitating medication induced dyskinesias , unpredictable “ off time ” state , and medication refractory tremor .
Medication refractory tremor and intolerable dyskinesia are potential palliative indications .
Medication refractory tremor and intolerable dyskinesia are potential palliative indications .
The main indications for PD DBS have traditionally been motor fluctuations , debilitating medication induced dyskinesias , unpredictable “ off time ” state , and medication refractory tremor .
To date , two main targets have emerged in PD patients : the globus pallidus pars interna and the subthalamic nucleus .
Two other targets , the ventralis intermedius and zona incerta have also been selectively used , especially in tremor - dominant PD patients .
Two other targets , the ventralis intermedius and zona incerta have also been selectively used , especially in tremor - dominant PD patients .
Deep brain stimulation ( DBS ) is considered a safe and well tolerated surgical procedure to alleviate Parkinson ’s disease ( PD ) and other movement disorders symptoms along with some psychiatric conditions .
Deep brain stimulation ( DBS ) is considered a safe and well tolerated surgical procedure to alleviate Parkinson ’s disease ( PD ) and other movement disorders symptoms along with some psychiatric conditions .
Deep brain stimulation ( DBS ) is considered a safe and well tolerated surgical procedure to alleviate Parkinson ’s disease ( PD ) and other movement disorders symptoms along with some psychiatric conditions .
Deep brain stimulation ( DBS ) is considered a safe and well tolerated surgical procedure to alleviate Parkinson ’s disease ( PD ) and other movement disorders symptoms along with some psychiatric conditions .
Deep brain stimulation ( DBS ) is considered a safe and well tolerated surgical procedure to alleviate Parkinson ’s disease ( PD ) and other movement disorders symptoms along with some psychiatric conditions .
Deep brain stimulation ( DBS ) is considered a safe and well tolerated surgical procedure to alleviate Parkinson ’s disease ( PD ) and other movement disorders symptoms along with some psychiatric conditions .
Deep brain stimulation ( DBS ) is considered a safe and well tolerated surgical procedure to alleviate Parkinson ’s disease ( PD ) and other movement disorders symptoms along with some psychiatric conditions .
Deep brain stimulation ( DBS ) is considered a safe and well tolerated surgical procedure to alleviate Parkinson ’s disease ( PD ) and other movement disorders symptoms along with some psychiatric conditions .
Deep brain stimulation ( DBS ) is considered a safe and well tolerated surgical procedure to alleviate Parkinson ’s disease ( PD ) and other movement disorders symptoms along with some psychiatric conditions .
Deep brain stimulation ( DBS ) is considered a safe and well tolerated surgical procedure to alleviate Parkinson ’s disease ( PD ) and other movement disorders symptoms along with some psychiatric conditions .
To date , two main targets have emerged in PD patients : the globus pallidus pars interna and the subthalamic nucleus .
Deep brain stimulation ( DBS ) is considered a safe and well tolerated surgical procedure to alleviate Parkinson ’s disease ( PD ) and other movement disorders symptoms along with some psychiatric conditions .
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