Update on augmentation of antidepressant response in resistant depression

@article{Debattista2005UpdateOA,
  title={Update on augmentation of antidepressant response in resistant depression},
  author={C. Debattista and A. Lembke},
  journal={Current Psychiatry Reports},
  year={2005},
  volume={7},
  pages={435-440}
}
Most patients in acute depression trials fail to achieve remission with antidepressant monotherapy. Many patients seem to require more than one medication to achieve remission or adequate response. Augmentation strategies are commonly used in clinical practice, but most have been poorly studied. In addition, better-studied strategies, such as the use of lithium and thyroid augmentation, have not been well investigated in combination with newer antidepressants. Various novel strategies are being… Expand
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