Update on Signal Transduction Regulation of the Heat-Shock Response

  title={Update on Signal Transduction Regulation of the Heat-Shock Response},
  author={Fritz Sch{\"o}ffl and Ralf Pr{\"a}ndl and Andreas P. Reindl},
The heat-shock response is a conserved reaction of cells and organisms to elevated temperatures (heat shock or heat stress). Whereas severe heat stress leads to cellular damage and cell death, sublethal doses of heat stress induce a cellular response, the heat-shock response, which (a) protects cells and organisms from severe damage, (b) allows resumption of normal cellular and physiological activities, and (c) leads to a higher level of thermotolerance. Crucial to the survival of cells is the… CONTINUE READING

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