Update on Raloxifene: Mechanism of Action, Clinical Efficacy, Adverse Effects, and Contraindications

@article{Gizzo2013UpdateOR,
  title={Update on Raloxifene: Mechanism of Action, Clinical Efficacy, Adverse Effects, and Contraindications},
  author={S. Gizzo and C. Saccardi and T. S. Patrelli and R. Berretta and G. Capobianco and S. Gangi and Antonio Vacilotto and A. Bertocco and M. Noventa and E. Ancona and D. D'antona and G. Nardelli},
  journal={Obstetrical & Gynecological Survey},
  year={2013},
  volume={68},
  pages={467–481}
}
Raloxifene is the only selective estrogen receptor modulator approved for long-term treatment in the prevention of osteoporotic fractures and for the reduction of invasive breast cancer risk in postmenopausal women. The demonstrated beneficial effects on bone and mammalian tissue led clinical and molecular research to focus mainly on these organs, giving less attention to all other systemic effects. The aim of this review was to evaluate all described systemic effects of raloxifene… Expand
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