Update on High-Altitude Pulmonary Edema: Pathogenesis, Prevention, and Treatment

@inproceedings{Stream2008UpdateOH,
  title={Update on High-Altitude Pulmonary Edema: Pathogenesis, Prevention, and Treatment},
  author={Joshua O Stream and C. Grissom},
  booktitle={Wilderness & environmental medicine},
  year={2008}
}
Abstract High-altitude pulmonary edema (HAPE) is a life-threatening noncardiogenic form of pulmonary edema (PE) that afflicts susceptible persons after rapid ascent to high altitude above 2500 m. Its pathogenesis is related to increased sympathetic tone, exaggerated hypoxic pulmonary vasoconstriction, uneven hypoxic pulmonary vasoconstriction with overperfusion of some regions of the pulmonary vascular bed, increased pulmonary capillary pressure, stress failure of pulmonary capillaries, and… Expand
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