Update of immune events in the murine contact hypersensitivity model: toward the understanding of allergic contact dermatitis.

@article{Honda2013UpdateOI,
  title={Update of immune events in the murine contact hypersensitivity model: toward the understanding of allergic contact dermatitis.},
  author={Tetsuya Honda and Gyohei Egawa and Stephan Grabbe and Kenji Kabashima},
  journal={The Journal of investigative dermatology},
  year={2013},
  volume={133 2},
  pages={303-15}
}
Allergic contact dermatitis (ACD) is one of the most common skin diseases, consisting of sensitization and elicitation phases. With the advancement of technology and the discovery of new types of immune cells, our knowledge of the immunological mechanisms of contact hypersensitivity (CHS) as a murine model of ACD has expanded significantly in the past decade. For example, by introducing regulatory T cells, CD4(+) T-helper 17 cells, and Langerin-positive dermal dendritic cells, the initiation… CONTINUE READING
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