Update in preimplantation genetic diagnosis: successes, advances, and problems.

@article{Grifo1996UpdateIP,
  title={Update in preimplantation genetic diagnosis: successes, advances, and problems.},
  author={Jamie A. Grifo and Ya Xu Tang and Santiago Munn{\'e} and Lewis C Krey},
  journal={Current opinion in obstetrics & gynecology},
  year={1996},
  volume={8 2},
  pages={135-8}
}
The field of preimplantation genetic diagnosis has undergone significant advances since the report of the first birth from this method in 1990. The first birth in the USA was reported in 1992, as was the first successful diagnosis and delivery of a baby free of a single gene defect disorder (cystic fibrosis and then Tay Sachs). Investigators have now reported approximately 40 births worldwide from preimplantation genetic diagnosis using the polymerase chain reaction and fluorescent in-situ… CONTINUE READING