Update from the latest WHO classification of MPNs: a user's manual.

@article{Passamonti2016UpdateFT,
  title={Update from the latest WHO classification of MPNs: a user's manual.},
  author={Francesco Passamonti and Margherita Maffioli},
  journal={Hematology. American Society of Hematology. Education Program},
  year={2016},
  volume={2016 1},
  pages={534-542}
}
The 2016 multiparameter World Health Organization (WHO) classification for Philadelphia-negative myeloproliferative neoplasms (MPNs) integrates clinical features, morphology, and genetic data to diagnose polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF). The main novelties are: (1) the reduction of the hemoglobin (Hb) level threshold to diagnose PV, now established at 16.5 g/dL for men and 16 g/dL for women (based on the identification of MPN patients with… CONTINUE READING