Update '96 on pulmonary gas exchange pathophysiology in pneumonia.

  title={Update '96 on pulmonary gas exchange pathophysiology in pneumonia.},
  author={Roberto Rodr{\'i}guez-Rois{\'i}n and Josep Roca},
  journal={Seminars in respiratory infections},
  volume={11 1},
The major determinant of abnormal pulmonary gas exchange in patients with pneumonia is characterized by marked increases in intrapulmonary shunt combined with mild to moderate ventilation-perfusion (VA/Q) inequalities. Other mechanisms influencing the levels of arterial hypoxemia, such as disequilibrium of alveolar to endcapillary oxygen diffusion or increased intrapulmonary parenchymal oxygen uptake, are trivial in the clinical arena. These pathophysiological findings mostly concur with the… CONTINUE READING