Combination therapy protects macaques against advanced Marburg virus disease
- MedicineNature communications
The benefit of combination therapy with a mAb and remdesivir in a non-human primate model of Marburg virus (MARV) disease is explored and value is suggested in exploring combination therapy in patients presenting with advanced filovirus disease.
Dietary Supplements and Nutraceuticals Under Investigation for COVID-19 Prevention and Treatment
- Biology, MedicineArXiv
In this review, the evidence surrounding dietary supplements and nutraceuticals for the prophylaxis and treatment of COVID-19 is critically appraised and it is indicated that vitamin D deficiency may be associated with greater incidence of infection and severity of CO VID-19.
Perspectives on the use and risk of adverse events associated with cytokine-storm targeting antibodies and challenges associated with development of novel monoclonal antibodies for the treatment of COVID-19 clinical cases
- MedicineHuman vaccines & immunotherapeutics
A perspective on antibody-based research efforts and their limitations for COVID-19 is presented and the affordability of novel mAbs across the global economic spectrum may seriously limit their accessibility.