Up-regulation of insulin-like growth factor axis components in human primary prostate cancer correlates with tumor grade.

@article{Liao2005UpregulationOI,
  title={Up-regulation of insulin-like growth factor axis components in human primary prostate cancer correlates with tumor grade.},
  author={Yongde Liao and Ulrich Abel and Rainer Grobholz and Alexander Hermani and Lutz Trojan and Peter Angel and Doris Mayer},
  journal={Human pathology},
  year={2005},
  volume={36 11},
  pages={1186-96}
}
There is an evidence that components of the insulin-like growth factor (IGF)-signaling pathway are involved in the development and progression of prostate cancer. The aim of the present study was to provide a comprehensive analysis of the expression levels of proteins of the IGF axis in prostate cancer. We studied expression of the ligands IGF-I and IGF-II, the inhibitory IGF binding protein-3, the type I IGF receptor (IGF-IR), and the downstream mediator insulin receptor substrate-1 by… CONTINUE READING
34 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 34 extracted citations

Similar Papers

Loading similar papers…