Up-regulation of glial cell line-derived neurotrophic factor (GDNF) following traumatic spinal cord injury.

@article{Satake2000UpregulationOG,
  title={Up-regulation of glial cell line-derived neurotrophic factor (GDNF) following traumatic spinal cord injury.},
  author={Katsusuke Satake and Yukihiro Matsuyama and Masao Kamiya and Hayato Kawakami and Hideaki Iwata and Kayo Adachi and Kazutoshi Kiuchi},
  journal={Neuroreport},
  year={2000},
  volume={11 17},
  pages={3877-81}
}
We investigated the temporal and spatial expression patterns of the GDNF gene after subjecting rats to an acute contusion injury of the spinal cord using the weight drop technique. Reverse transcriptase-polymerase chain reaction (RT-PCR) revealed that GDNF transcription in the spinal cord began to increase within 30 min after injury and peaked within 3 h… CONTINUE READING