Up-regulation of defense enzymes is responsible for low reactive oxygen species in malignant prostate cancer cells

@article{Lim2005UpregulationOD,
  title={Up-regulation of defense enzymes is responsible for low reactive oxygen species in malignant prostate cancer cells},
  author={Hye-won Lim and Suntaek Hong and W. Woody Jin and Seunghwan Lim and Su-Jung Kim and H. Kang and Eun-Hee Park and Kisup Ahn and C. -C. Lim},
  journal={Experimental & Molecular Medicine},
  year={2005},
  volume={37},
  pages={497-506}
}
Reactive oxygen species (ROS) are involved in a diversity of important phenomena in the process of tumor development. To investigate the alterations of oxidative stress and their related systems in tumor progression, a variety of components in the antioxidative stress defense system were examined in prostate cancer cell lines, PC3 and LNCaP. Cell surface molecules involved in metastasis were expressed highly in PC3 cells compared with LNCaP cells, and strong invasion ability was shown in PC3… CONTINUE READING
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