Up-regulation of adiponectin, its isoforms and receptors in end-stage kidney disease.

@article{Shen2007UpregulationOA,
  title={Up-regulation of adiponectin, its isoforms and receptors in end-stage kidney disease.},
  author={Yvonne Y Shen and John A. Charlesworth and John J P Kelly and Ken W. K. Loi and Philip W. Peake},
  journal={Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association},
  year={2007},
  volume={22 1},
  pages={
          171-8
        }
}
  • Yvonne Y Shen, J. Charlesworth, P. Peake
  • Published 27 September 2006
  • Medicine, Biology
  • Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
BACKGROUND Despite the favourable effects of adiponectin on the vasculature and insulin resistance (IR), levels are increased in patients with end-stage kidney disease (ESKD), in whom both IR and atherosclerosis are prevalent. METHODS To investigate this paradox, we examined the distribution of adiponectin isoforms, the expression of adiponectin receptor (AdipoR) mRNA on peripheral blood mononuclear cells (PBMC) in 41 patients with ESKD on haemodialysis and 41 matched controls, and its… 

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