Up-regulated desaturase and elongase gene expression promoted accumulation of polyunsaturated fatty acid (PUFA) but not long-chain PUFA in Lates calcarifer, a tropical euryhaline fish, fed a stearidonic acid- and γ-linoleic acid-enriched diet.

@article{Alhazzaa2011UpregulatedDA,
  title={Up-regulated desaturase and elongase gene expression promoted accumulation of polyunsaturated fatty acid (PUFA) but not long-chain PUFA in Lates calcarifer, a tropical euryhaline fish, fed a stearidonic acid- and γ-linoleic acid-enriched diet.},
  author={Ramez Alhazzaa and Andrew R. Bridle and Peter David Nichols and Chris G. Carter},
  journal={Journal of agricultural and food chemistry},
  year={2011},
  volume={59 15},
  pages={8423-34}
}
The limited activity of Δ6 fatty acid desaturase (FAD6) on α-linolenic (ALA, 18:3n-3) and linoleic (LA, 18:2n-6) acids in marine fish alters the long-chain (≥C(20)) polyunsaturated fatty acid (LC-PUFA) concentration in fish muscle and liver when vegetable oils replace fish oil (FO) in aquafeeds. Echium oil (EO), rich in stearidonic acid (SDA, 18:4n-3) and γ-linoleic acid (GLA, 18:3n-6), may enhance the biosynthesis of n-3 and n-6 LC-PUFA by bypassing the rate-limiting FAD6 step. Nutritional and… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 62 references

Characterization and modulation of gene expression and enzymatic activity of Δ - 6 desaturase in teleosts : a review

  • M. Vagner, E. Santigosa
  • Aquaculture
  • 2011

Replacing dietary fi sh oil with Echium oil enriched barramundi with C 18 PUFA rather than long - chain PUFA

  • R. Alhazzaa, A. R. Bridle, P. D. Nichols, C. G. Carter
  • Aquaculture
  • 2011

A determination of the quantitative requirements for docosahexaenoic acid for juvenile barramundi ( Lates calcarifer )

  • B. Glencross, N. Rutherford
  • Aquacult . Nutr .
  • 2010

E ff ects of dietary fi sh oil substitution by Echium oil on enterocyte and hepatocyte lipid metabolism of gilthead seabream ( Sparus aurata L . )

  • M. J. erez, N. G. Acosta, +4 authors C. Rodríguez
  • Comp . Biochem . Physiol . B : Biochem . Mol…
  • 2010

Similar Papers

Loading similar papers…