Up-front Hepatic Resection for Metastatic Colorectal Cancer Results in Favorable Long-term Survival

@article{Nanji2012UpfrontHR,
  title={Up-front Hepatic Resection for Metastatic Colorectal Cancer Results in Favorable Long-term Survival},
  author={S. Nanji and S. Cleary and P. Ryan and M. Guindi and Subani Selvarajah and P. Grieg and I. Mcgilvary and B. Taylor and A. Wei and C. Moulton and S. Gallinger},
  journal={Annals of Surgical Oncology},
  year={2012},
  volume={20},
  pages={295-304}
}
  • S. Nanji, S. Cleary, +8 authors S. Gallinger
  • Published 2012
  • Medicine
  • Annals of Surgical Oncology
  • BackgroundHepatic metastasis from colorectal cancer (CRC) is best managed with a multimodal approach; however, the optimal timing of liver resection in relation to administration of perioperative chemotherapy remains unclear. Our strategy has been to offer up-front liver resection for patients with resectable hepatic metastases, followed by post–liver resection chemotherapy. We report the outcomes of patients based on this surgical approach.MethodsA retrospective review of all patients… CONTINUE READING
    49 Citations
    Surgical resection and peri-operative chemotherapy for colorectal cancer liver metastases: A population-based study.
    • 14
    Liver resection after chemotherapy and tumour downsizing in patients with initially unresectable colorectal cancer liver metastases.
    • 15
    Regional lymph node involvement in patients undergoing liver resection for colorectal cancer metastases.
    • S. Nanji, M. Tsang, X. Wei, C. Booth
    • Medicine
    • European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
    • 2017
    • 9
    Chemotherapy delivery for resected colorectal cancer liver metastases: Management and outcomes in routine clinical practice.
    • 7
    Determinants of Long-Term Outcome in Patients Undergoing Simultaneous Resection of Synchronous Colorectal Liver Metastases
    • 10
    • PDF

    References

    SHOWING 1-10 OF 34 REFERENCES
    Outcome After Hepatectomy for Multiple (Four or More) Colorectal Metastases in the Era of Effective Chemotherapy
    • 151
    Adjuvant chemotherapy improves survival after resection of hepatic colorectal metastases: analysis of data from two continents.
    • 175
    Neoadjuvant chemotherapy before liver resection for patients with unresectable liver metastases from colorectal carcinoma.
    • 282
    Resection of hepatic metastases from colorectal cancer
    • 149
    Surgical Resection of Colorectal Liver Metastases in Patients with Expanded Indications: A Single-Center Experience with 501 Patients
    • 124
    Improved survival in metastatic colorectal cancer is associated with adoption of hepatic resection and improved chemotherapy.
    • 953
    A study of prognostic factors for hepatic resection for colorectal metastases.
    • 185