Unwinding of heterologous DNA by RecA protein during the search for homologous sequences.

@article{Rould1992UnwindingOH,
  title={Unwinding of heterologous DNA by RecA protein during the search for homologous sequences.},
  author={E Rould and K. Muniyappa and C. M. Radding},
  journal={Journal of molecular biology},
  year={1992},
  volume={226 1},
  pages={127-39}
}
The search for homologous sequences promoted by RecA protein in vitro involves a presynaptic filament and naked duplex DNA, the multiple contacts of which produce nucleoprotein networks or coaggregates. The single-stranded DNA within the presynaptic filaments, however, is extended to an axial spacing 1.5 times that of B-form DNA. To investigate this paradoxical difference between the spacing of bases in the RecA presynaptic filament versus the target duplex DNA, we explored the effect of… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 16 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 31 references

Transcription generates positively and negatively supercoiled domains

H. Wu, S. Shyy, J. C. Wang, L Liu
in the template. Cell, • 1988

Visualization of the paranemic joining of homologous DNA molecules catalyzed by the RecA protein of Escherichia coli.

Proceedings of the National Academy of Sciences of the United States of America • 1986
View 1 Excerpt

Similar Papers

Loading similar papers…