Unwinding-like activity associated with avian retrovirus RNA-directed DNA polymerase.

@article{Collett1978UnwindinglikeAA,
  title={Unwinding-like activity associated with avian retrovirus RNA-directed DNA polymerase.},
  author={Marc S. Collett and J P Leis and Marilyn S. Smith and Anthony J. Faras},
  journal={Journal of virology},
  year={1978},
  volume={26 2},
  pages={498-509}
}
The avian retrovirus RNA-directed DNA polymerase contains an activity that is capable of removing hydrogen bonds from duplex nucleic acid molecules. This "unwinding-like" activity appears to be specific in its action, affecting RNA.DNA and DNA.DNA duplex molecules but not RNA.RNA duplexes. Studies with defined RNA.DNA hybrid molecules (e.g., Rous sarcoma virus RNA and complementary DNAs representing specific regions of the Rous sarcoma virus genome) and DNA.DNA duplexes indicate that, although… CONTINUE READING