Unveiling viral-host interactions within the 'microbial dark matter'.

@article{MartinezGarcia2014UnveilingVI,
  title={Unveiling viral-host interactions within the 'microbial dark matter'.},
  author={Manuel Martinez-Garcia and Fernando J. V. Santos and Mercedes Moreno-Paz and Victor Parro and J. M. Garc{\'i}a Ant{\'o}n},
  journal={Nature communications},
  year={2014},
  volume={5},
  pages={4542}
}
Viruses control natural microbial communities. Identification of virus-host pairs relies either on their cultivation or on metagenomics and tentative assignment based on genomic signatures. Both approaches have severe drawbacks when aiming to target such pairs within the uncultured majority. Here we present an unambiguous way to assign viruses to hosts that does not rely on any previous information about either of them nor requires their cultivation. First, genomic contents of individual cells… CONTINUE READING
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