Unveiling the establishment of left–right asymmetry in the chick embryo

@article{Raya2004UnveilingTE,
  title={Unveiling the establishment of left–right asymmetry in the chick embryo},
  author={{\'A}ngel Raya and Juan Carlos Izpisua Belmonte},
  journal={Mechanisms of Development},
  year={2004},
  volume={121},
  pages={1043-1054}
}
Vertebrates display striking left-right asymmetries in the placement of internal organs, which are concealed by a seemingly bilaterally symmetric body plan. The establishment of asymmetries about the left-right axis occurs early during embryo development and requires the concerted and sequential action of several epigenetic, genetic and cellular mechanisms. Experiments in the chick embryo model have contributed crucially to our current understanding of such mechanisms and are reviewed here… Expand
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