Unusually large telomeric repeats in the yeast Candida albicans.

  title={Unusually large telomeric repeats in the yeast Candida albicans.},
  author={Michael J. McEachern and James B. Hicks},
  journal={Molecular and cellular biology},
  volume={13 1},
We have identified sequences at the telomeres of the yeast Candida albicans and have found that they are composed of tandem copies of a 23-bp sequence. Through the cloning of native telomeric ends and the characterization and cloning of a "healed" end, we demonstrate that these repeated sequences are sufficient to function as a telomere. All copies of the 23-bp repeat that have been sequenced from a number of C. albicans strains are identical. In contrast, adjacent subtelomeric sequences are… CONTINUE READING