Unusual thyroid tumors: a review of pathologic and molecular diagnosis.

@article{Hunt2005UnusualTT,
  title={Unusual thyroid tumors: a review of pathologic and molecular diagnosis.},
  author={Jennifer Leigh Hunt},
  journal={Expert review of molecular diagnostics},
  year={2005},
  volume={5 5},
  pages={725-34}
}
The most common thyroid neoplasms are either follicular derived (papillary, follicular and Hürthle cell lesions) or C-cell derived (medullary carcinoma). The diagnosis of these tumors can usually be made at the histologic level, with immunohistochemical stains necessary in some circumstances. Specific molecular mutations have been described that can be diagnostically useful or explain, in part, their pathogenesis, including the well-known Ret/PTC and PPARgamma-PAX8 translocations, point… CONTINUE READING