Unusual macular lesions in a patient with neurofibromatosis type-1


Background. Retinal involvement in neurofibromatosis type-1 (NF-1) is rare. Methods. We present a case report of a 49-year-old man with neurofibromatosis who developed bilateral macular lesions associated with gradual reduction of visual acuity. Results. Electrophysiology revealed an absent pattern electroretinogram. Fluorescein angiography demonstrated mottled hyperfluorescence of the maculae in the early-phase fluorescein angiogram followed by late staining of the lesions. Conclusions. Our patient had unusual bilateral macular lesions which had some features suggestive of adult-onset foveomacular vitelliform dystrophy. To the best of our knowledge, there have been no previous reports of such macular lesions occurring in association with NF-1.

DOI: 10.1007/s10792-006-9002-0

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@article{McLoone2005UnusualML, title={Unusual macular lesions in a patient with neurofibromatosis type-1}, author={Eibhlin McLoone and Trevor A. S. Buchanan}, journal={International Ophthalmology}, year={2005}, volume={26}, pages={115-117} }