Unusual isomeric corniculatolides from mangrove, Aegiceras corniculatum.

  title={Unusual isomeric corniculatolides from mangrove, Aegiceras corniculatum.},
  author={Mangala Gowri Ponnapalli and Suresh Annam and Saidulu Ravirala and Sushma Sukki and Madhu Ankireddy and Venugopal Raju Tuniki},
  journal={Journal of natural products},
  volume={75 2},
Four new isomeric macrolides of combretastatin D-2 congeners named isocorniculatolide A (1), 11-O-methylisocorniculatolide A (2), 11-O-methylcorniculatolide A (3), and 12-hydroxy-11-O-methylcorniculatolide A (4), and the known corniculatolide A (5), arjunolic acid, and maslinic acid were isolated from the CHCl(3) extract of the bark of Aegiceras corniculatum. The structures of the new compounds (1-4) were elucidated by a combination of spectroscopic analysis (1-5), chemical modifications, and… 
12-Hydroxycorniculatolide a from the Mangrove Tree, Lumnitzera littorea
A new macrocyclic lactone, 12-hydroxycorniculatolide A (1), along with three known compounds, corniculatolide A (2), 12-hydroxy-11-O-methyl-corniculatolide A (3) and 6,7-dimethoxycoumarin (4) were
α-Glucosidase Inhibitory Isomeric Corniculatolides from the Stems of the Indian Mangrove Plant, Xylocarpus granatum.
Three new isomeric corniculatolides with an unusual caffrane and isocorniculane framework, and five known metabolites were isolated from the chloroform extract of the stems of Xylocarpus granatum, showing no effect on the mammalian cancer cell lines MIAPaCa-2, DU145, MCF-7, and HTC-116.
Isomeric ent‐Labdane‐Type Diterpenoids from the Stems of Rhizophora mucronata
Two new constitutional isomers of ent-labdane-type diterpenoids, 1 and 2, with an unusual seven-membered lactone moiety (i.e., 1), together with two known compounds, 3 and 4, were isolated from the
A new resorcinol derivative from the bark of Aegiceras floridum (Primulaceae)
The cytotoxic activity of selected isolated compounds against some cancer cell lines such as human epithelial carcinoma, human lung cancer, NCI-H460, liver hepatocellular carcinoma (HepG2), human breast cancer (MCF-7), and acute T cell leukemia (Jurkat) was evaluated.
Self gelating isoracemosol A, new racemosaceramide A, and racemosol E from Barringtonia racemosa
Phytochemical investigation into the CHCl3 extract of the fruits of Barringtonia racemosa resulted in the isolation of two new metabolites along with isoracemosol A and betulinic acid as known metabolites, which leads to the unexpected agglomerated porous-like morphology.


Excoecarins D, E, and K, from excoecaria agallocha.
Three novel diterpenoids, excoecarins D, E, and K (1-3), were isolated from Excoecaria agallocha on the basis of extensive NMR experiments and by X-ray analysis.
Combretastatins D-3 and D-4, new macrocyclic lactones from Getonia floribunda.
Two new macrocyclic lactones, combretastatins D-3 and D-4, were isolated from Getonia floribunda and showed weak antitubercular activity with a minimum inhibitory concentration of 100.0 microg/mL, and was inactive towards the malarial parasite.
Antineoplastic agents. 206. Structure of the cytostatic macrocyclic lactone combretastatin D-2
The South African tree Combretum caffrum (Combretaceae) has been found to contain two new and cytostatic (P388 lymphocytic leukemia) macrocyclic lactones designated combretastatin D-1 (1, ED 50 3.3
Antineoplastic agents. 565. Synthesis of combretastatin D-2 phosphate and dihydro-combretastatin D-2.
A parallel first total synthesis of dihydro-combretastatin D-2 was completed, proceeding from a saturated 3-phenylpropionic ester intermediate via the Ullmann biaryl ether reaction.
Ceriopsin E, a new epoxy ent-kaurene diterpenoid from Ceriops decandra.
A new epoxy ent-kaurene diterpenoid, ceriopsin E (1), has been isolated from the mangrove plant Ceriops decandra and its structure elucidated by spectral data and single-crystal X-ray analysis.