Unusual isomeric corniculatolides from mangrove, Aegiceras corniculatum.

@article{Ponnapalli2012UnusualIC,
  title={Unusual isomeric corniculatolides from mangrove, Aegiceras corniculatum.},
  author={Mangala Gowri Ponnapalli and Suresh Annam and Saidulu Ravirala and Sushma Sukki and Madhu Ankireddy and Venugopal Raju Tuniki},
  journal={Journal of natural products},
  year={2012},
  volume={75 2},
  pages={
          275-9
        }
}
Four new isomeric macrolides of combretastatin D-2 congeners named isocorniculatolide A (1), 11-O-methylisocorniculatolide A (2), 11-O-methylcorniculatolide A (3), and 12-hydroxy-11-O-methylcorniculatolide A (4), and the known corniculatolide A (5), arjunolic acid, and maslinic acid were isolated from the CHCl(3) extract of the bark of Aegiceras corniculatum. The structures of the new compounds (1-4) were elucidated by a combination of spectroscopic analysis (1-5), chemical modifications, and… 
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23 Citations

12-Hydroxycorniculatolide a from the Mangrove Tree, Lumnitzera littorea
A new macrocyclic lactone, 12-hydroxycorniculatolide A (1), along with three known compounds, corniculatolide A (2), 12-hydroxy-11-O-methyl-corniculatolide A (3) and 6,7-dimethoxycoumarin (4) were…
α-Glucosidase Inhibitory Isomeric Corniculatolides from the Stems of the Indian Mangrove Plant, Xylocarpus granatum.
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Three new isomeric corniculatolides with an unusual caffrane and isocorniculane framework, and five known metabolites were isolated from the chloroform extract of the stems of Xylocarpus granatum, showing no effect on the mammalian cancer cell lines MIAPaCa-2, DU145, MCF-7, and HTC-116.
Synthesis of isomeric corniculatolides
A new macrocyclic lactone and a new quinoflavan from Celastrus hindsii
Isomeric ent‐Labdane‐Type Diterpenoids from the Stems of Rhizophora mucronata
Two new constitutional isomers of ent-labdane-type diterpenoids, 1 and 2, with an unusual seven-membered lactone moiety (i.e., 1), together with two known compounds, 3 and 4, were isolated from the…
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Unusual ent-isopimarane-type diterpenoids from the wood of Excoecaria agallocha
A new resorcinol derivative from the bark of Aegiceras floridum (Primulaceae)
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The cytotoxic activity of selected isolated compounds against some cancer cell lines such as human epithelial carcinoma, human lung cancer, NCI-H460, liver hepatocellular carcinoma (HepG2), human breast cancer (MCF-7), and acute T cell leukemia (Jurkat) was evaluated.
Self gelating isoracemosol A, new racemosaceramide A, and racemosol E from Barringtonia racemosa
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Phytochemical investigation into the CHCl3 extract of the fruits of Barringtonia racemosa resulted in the isolation of two new metabolites along with isoracemosol A and betulinic acid as known metabolites, which leads to the unexpected agglomerated porous-like morphology.
Applications of Mitsunobu Reaction in total synthesis of natural products
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