Unusual immunophenotype of T-cell large granular lymphocytic leukemia: report of two cases.

@article{Rabade2015UnusualIO,
  title={Unusual immunophenotype of T-cell large granular lymphocytic leukemia: report of two cases.},
  author={Nikhil R Rabade and Dia Mansukhani and Shanaz Khodaiji and Balkrishna Padte and Abhay A Bhave and Prashant R Tembhare and Papagudi Ganesan Subramanian and Kunal K Sehgal},
  journal={Indian journal of pathology & microbiology},
  year={2015},
  volume={58 1},
  pages={108-12}
}
Large granular lymphocytes (LGL) leukemias are commonly of the T-cell or NK-cell type. T-cell LGL leukemia is typically a disorder of mature CD3, CD8 and T-cell receptor TCR (TCR - T cell receptor)-αβ positive cytotoxic T-cells. Rare variants include TCRγδ+ variants and CD4 + TCRαβ+ cases. We report a case of each of these rare variants. An 83-year-old… CONTINUE READING