Unusual deregulation of cell cycle components in early and frank estrogen-induced renal neoplasias in the Syrian hamster.

@article{Liao2000UnusualDO,
  title={Unusual deregulation of cell cycle components in early and frank estrogen-induced renal neoplasias in the Syrian hamster.},
  author={D. Z. Liao and Xianghua Hou and Shu-fang Bai and Sara Antonia Li and Jonathan S. Li},
  journal={Carcinogenesis},
  year={2000},
  volume={21 12},
  pages={2167-73}
}
There is strong evidence that estrogens are involved in the etiology, promotion and progression of a variety of cancers, including the cancers of the breast and endometrium. The Syrian hamster estrogen-induced, estrogen-dependent renal neoplasm is a well-established animal model used to elucidate the cellular and molecular mechanisms involved in solely estrogen-induced carcinogenic processes. G(1) cell cycle progression was studied in estrogen-induced early renal tumor foci and in large kidney… CONTINUE READING
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