Unusual contact allergens from plants in the family Hydrophyllaceae

@article{Reynolds1986UnusualCA,
  title={Unusual contact allergens from plants in the family Hydrophyllaceae},
  author={Gary W. Reynolds and William L. Epstein and Eloy Rodr{\'i}guez},
  journal={Contact Dermatitis},
  year={1986},
  volume={14}
}
The dermatitic constituents of the glandular hairs of plants in the family Hydrophyllaceae comprise a class of uncommon natural products called “phacelioids”. The chemical structures consist of various elaborations of hydroquinone attached to a C10 to C20 prenyl chain. Certain of these compounds are equivalent to the urushiols of Toxicadendron (Rhus) in their capacity to sensitize humans. Although structurally related to the urushiols, the phacelioids do not appear to cross‐react in humans… 
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