Unusual chromatin in human telomeres.

  title={Unusual chromatin in human telomeres.},
  author={H. Tommerup and Athanasios G. Dousmanis and Titia de Lange},
  journal={Molecular and cellular biology},
  volume={14 9},
We report that human telomeres have an unusual chromatin structure characterized by diffuse micrococcal nuclease patterns. The altered chromatin manifested itself only in human telomeres that are relatively short (2 to 7 kb). In contrast, human and mouse telomeres with telomeric repeat arrays of 14 to 150 kb displayed a more canonical chromatin structure with extensive arrays of tightly packed nucleosomes. All telomeric nucleosomes showed a shorter repeat size than bulk nucleosomes, and… CONTINUE READING

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