Unusual association of multiple sclerosis and tomaculous neuropathy.

  title={Unusual association of multiple sclerosis and tomaculous neuropathy.},
  author={Jelena S. Drulovi{\'c} and Slobodan Dozi{\'c} and Zvonimir Levi{\'c} and Neboj{\vs}a Stojsavljevi{\'c} and Rajko Triki{\'c} and Dubravka Cvetkovi{\'c} and Slobodan A Apostolski},
  journal={Journal of the neurological sciences},
  volume={157 2},
We describe two cases in which multiple sclerosis (MS) occurred in association with tomaculous neuropathy, presenting as chronic, distal sensorimotor polyneuropathy. In Case 1, monoclonal gammopathy of undetermined significance with monoclonal IgG lambda reactive against GM1 ganglioside, was also detected. The diagnosis of tomaculous neuropathy was established after sural nerve biopsy. Teased fibers examination revealed focal 'sausage-like' thickenings of the myelin sheaths in intact fibers and… CONTINUE READING