Unusual Ratio between Free Thyroxine and Free Triiodothyronine in a Long-Lived Mole-Rat Species with Bimodal Ageing

@article{Henning2014UnusualRB,
  title={Unusual Ratio between Free Thyroxine and Free Triiodothyronine in a Long-Lived Mole-Rat Species with Bimodal Ageing},
  author={Y. Henning and Christiane Vole and S. Begall and Martin Bens and M. Broecker-Preuss and A. Sahm and K. Szafranski and H. Burda and P. Dammann},
  journal={PLoS ONE},
  year={2014},
  volume={9}
}
Ansell's mole-rats (Fukomys anselli) are subterranean, long-lived rodents, which live in eusocial families, where the maximum lifespan of breeders is twice as long as that of non-breeders. Their metabolic rate is significantly lower than expected based on allometry, and their retinae show a high density of S-cone opsins. Both features may indicate naturally low thyroid hormone levels. In the present study, we sequenced several major components of the thyroid hormone pathways and analyzed free… Expand
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