Untying the Gordian Knot of Cytokinesis

  title={Untying the Gordian Knot of Cytokinesis},
  author={Sergei N. Prokopenko and Robert B. Saint and Hugo J. Bellen},
  journal={The Journal of Cell Biology},
  pages={843 - 848}
Ability to divide is one of the basic properties of a cell. In metazoans, where cells divide in a context of germ layers, tissues, and organs, cell proliferation must be coordinated with differentiation to prevent developmental abnormalities. Genetic analyses in simple model systems (yeast, slime mold, fruit fly) have demonstrated that defects in either karyokinesis, or nuclear division (e.g., mutations that affect cell cycle checkpoints, mitotic chromosome condensation and segregation, etc… CONTINUE READING
Highly Cited
This paper has 34 citations. REVIEW CITATIONS


Publications citing this paper.
Showing 1-10 of 16 citations


Publications referenced by this paper.
Showing 1-10 of 46 references