Untranslated regions of diverse plant viral RNAs vary greatly in translation enhancement efficiency

  title={Untranslated regions of diverse plant viral RNAs vary greatly in translation enhancement efficiency},
  author={Qiuling Fan and Krzysztof Treder and W. Allen Miller},
  booktitle={BMC biotechnology},
BACKGROUND Whole plants or plant cell cultures can serve as low cost bioreactors to produce massive amounts of a specific protein for pharmacological or industrial use. To maximize protein expression, translation of mRNA must be optimized. Many plant viral RNAs harbor extremely efficient translation enhancers. However, few of these different translation elements have been compared side-by-side. Thus, it is unclear which are the most efficient translation enhancers. Here, we compare the effects… CONTINUE READING
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Pestova TV: The mechanism of eukaryotic translation initiation and principles of its regulation

  • RJ Jackson, CU Hellen
  • Nat Rev Mol Cell Biol
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