Until Death Do Us Part: Necrosis and Oxidation Promote the Tumor Microenvironment.


Tumor proliferation is concomitant with autophagy, limited apoptosis, and resultant necrosis. Necrosis is associated with the release of damage-associated molecular pattern molecules (DAMPs), which act as 'danger signals', recruiting inflammatory cells, inducing immune responses, and promoting wound healing. Most of the current treatment strategies for… (More)
DOI: 10.1159/000444941

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