Unsupervised parameter optimization for automated retention time alignment of severely shifted gas chromatographic data using the piecewise alignment algorithm.

@article{Pierce2007UnsupervisedPO,
  title={Unsupervised parameter optimization for automated retention time alignment of severely shifted gas chromatographic data using the piecewise alignment algorithm.},
  author={Karisa M Pierce and Bob W Wright and Robert E Synovec},
  journal={Journal of chromatography. A},
  year={2007},
  volume={1141 1},
  pages={106-16}
}
Simulated chromatographic separations were used to study the performance of piecewise retention time alignment and to demonstrate automated unsupervised (without a training set) parameter optimization. The average correlation coefficient between the target chromatogram and all remaining chromatograms in the data set was used to optimize the alignment… CONTINUE READING