Unsuccessful treatment of missed abortion with a combination of an antiprogesterone and a prostaglandin E1 analogue.

@article{Nielsen1997UnsuccessfulTO,
  title={Unsuccessful treatment of missed abortion with a combination of an antiprogesterone and a prostaglandin E1 analogue.},
  author={Signe Sofie Nielsen and M Hahlin and J-J Platz-Christensen},
  journal={British journal of obstetrics and gynaecology},
  year={1997},
  volume={104 9},
  pages={1094-6}
}
In a prospective clinical trial the effectiveness of a combination of 400 mg of mifepristone (antiprogesterone) and 400 g misoprostol (synthetic prostaglandin E1 analogue), both taken orally, was evaluated for the treatment of missed abortion. Of the 31 patients included, 16 (52%) had an empty uterine cavity at follow up six days after inclusion, 11 (35%) required surgical evacuation for retained intrauterine products of conception found at follow up, and four (13%) required emergency surgical… CONTINUE READING

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