Unstable, low-level transmission of malaria on the Colombian Pacific Coast.

@article{Gonzlez1997UnstableLT,
  title={Unstable, low-level transmission of malaria on the Colombian Pacific Coast.},
  author={J M Gonz{\'a}lez and V{\'i}ctor Alberto Olano and J. Dassel de Vergara and Myriam Ar{\'e}valo-Herrera and Gabriel Carrasquilla and S{\'o}crates Herrera and Jose Alejandro Poveda Lopez},
  journal={Annals of tropical medicine and parasitology},
  year={1997},
  volume={91 4},
  pages={349-58}
}
The development of immune responses to malarial infection in inhabitants of endemic areas differs according to the level of exposure to the parasite. Adults living in a region where the level of malaria transmission is low (Colombia) have been shown to exhibit a similar response to each of the three regions of the circumsporozoite protein (the central repeated NANP region, and the flanking N- and C-termini). Conversely, donors exposed to a frequent sporozoite challenge in areas of high malaria… CONTINUE READING