Unrestricted somatic stem cells (USSC) from human umbilical cord blood display uncommitted epigenetic signatures of the major stem cell pluripotency genes.

Abstract

Unrestricted somatic stem cells (USSC) from human cord blood display a broad differentiation potential for ectodermal, mesodermal, and endodermal cell types. The molecular basis for these stem cell properties is unclear and unlike embryonic stem cells (ESC) none of the major stem cell factors OCT4, SOX2, and NANOG exhibits significant expression in USSC… (More)
DOI: 10.1016/j.scr.2010.08.003

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Cite this paper

@article{Santourlidis2011UnrestrictedSS, title={Unrestricted somatic stem cells (USSC) from human umbilical cord blood display uncommitted epigenetic signatures of the major stem cell pluripotency genes.}, author={Simeon Santourlidis and Peter Wernet and Foued Ghanjati and Nina Graffmann and Judith D. Springer and Christian Silvester Kriegs and Xiaoyi Zhao and Jens Brands and Marcos J. Ara{\'u}zo-Bravo and Rui P L Neves and Gesine Koegler and Markus Uhrberg}, journal={Stem cell research}, year={2011}, volume={6 1}, pages={60-9} }