Unrestricted lineage differentiation of parthenogenetic ES cells

  title={Unrestricted lineage differentiation of parthenogenetic ES cells},
  author={Karin S. Sturm and Christoph Berger and Sheila X. Zhou and Sally L. Dunwoodie and S Z Tan and Patrick P. L. Tam},
  journal={Development Genes and Evolution},
 The developmental potential of parthenogenetic embryonic stem (P-ES) cells was studied in teratomas and mouse chimaeras. Teratomas derived from P-ES cells contained a mixture of tissue types with variable proportions of specific tissues. Three of the eight P-ES cell lines analysed showed high proportions of striated muscle in teratomas, similar to teratomas from normal embryos or ES cell lines derived from fertilised embryos (F-ES cells). Our study also revealed that one P-ES cell line showed… CONTINUE READING
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