Unrestricted killer cells recognize an antigen controlled by a gene linked toTla

@article{Lindahl2005UnrestrictedKC,
  title={Unrestricted killer cells recognize an antigen controlled by a gene linked toTla},
  author={Kirsten Fischer Lindahl},
  journal={Immunogenetics},
  year={2005},
  volume={8},
  pages={71-76}
}
Normal mouse lymphocytes readily generate a cytotoxic T-cell response in vitro against lymphocytes carrying foreign antigens determined by the H-2K, H-2D, and H-2L loci of the mouse major histocompatibility complex (Alter et al. 1973, Blanden and Kees 1978, Hansen and Levy 1978). A cytotoxic T-cell response to minor histocompatibility (H) antigens determined by genes not linked to the H-2 complex can usually be detected only after immunization in vivo followed by restimulation in vitro with H-2… CONTINUE READING
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