Unresolved orthology and peculiar coding sequence properties of lamprey genes: the KCNA gene family as test case

@inproceedings{Qiu2010UnresolvedOA,
  title={Unresolved orthology and peculiar coding sequence properties of lamprey genes: the KCNA gene family as test case},
  author={Huan Qiu and Falk Hildebrand and Shigehiro Kuraku and Axel Meyer},
  booktitle={BMC Genomics},
  year={2010}
}
In understanding the evolutionary process of vertebrates, cyclostomes (hagfishes and lamprey) occupy crucial positions. Resolving molecular phylogenetic relationships of cyclostome genes with gnathostomes (jawed vertebrates) genes is indispensable in deciphering both the species tree and gene trees. However, molecular phylogenetic analyses, especially those including lamprey genes, have produced highly discordant results between gene families. To efficiently scrutinize this problem using… CONTINUE READING