Unrecognized pretransplant and donor‐derived cryptococcal disease in organ transplant recipients.

  title={Unrecognized pretransplant and donor‐derived cryptococcal disease in organ transplant recipients.},
  author={H Sun and Barbara Dudley Alexander and Olivier Lortholary and Françoise Dromer and Graeme N. Forrest and G. Marshall Lyon and Jyoti Somani and Krishan Lal Gupta and Ramon del Busto and Timothy L. Pruett and Costi D Sifri and Ajit P Limaye and George Tharayil John and Goran B. G. Klintmalm and Kenneth J Pursell and Valentina Stosor and Michele Ileana Morris and Lorraine A Dowdy and Patricia Mu{\~n}oz and Andre C. Kalil and Julia B Garcia-Diaz and Susan L. Orloff and Andrew A. House and Sally H Houston and Dannah Wray and Shirish S. Huprikar and Leonard B Johnson and Atul Humar and Raymund Rabe Razonable and Robert A. Fisher and S Hamid Husain and Marilyn M. Wagener and N Heramani Singh},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  volume={51 9},
BACKGROUND Cryptococcosis occurring ≤30 days after transplantation is an unusual event, and its characteristics are not known. METHODS Patients included 175 solid-organ transplant (SOT) recipients with cryptococcosis in a multicenter cohort. Very early-onset and late-onset cryptococcosis were defined as disease occurring ≤30 days or >30 days after transplantation, respectively. RESULTS Very early-onset disease developed in 9 (5%) of the 175 patients at a mean of 5.7 days after… CONTINUE READING