Unravelling fungal immunity through primary immune deficiencies.

  title={Unravelling fungal immunity through primary immune deficiencies.},
  author={Desa Lili{\'c}},
  journal={Current opinion in microbiology},
  volume={15 4},
Fungal infections affect individuals with an impaired immune system and are on the increase, often with serious consequences. Recent studies in patients with primary immune deficiencies (PIDs) have led to important breakthroughs in our understanding of the different, mutually exclusive pathways underlying immunity to mucocutaneous as opposed to invasive fungal infections. Patients with defects affecting segments of innate (dectin-1, CARD9, IL12RB1) or adaptive immunity (interleukin (IL)17-F, IL… CONTINUE READING
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