Unraveling the role of myosin in forming autophagosomes.

  title={Unraveling the role of myosin in forming autophagosomes.},
  author={Hong-Wen Tang and Guang-Chao Chen},
  volume={7 7},
Macroautophagy (hereafter autophagy) is a membrane-mediated catabolic process that occurs in response to a variety of intra- and extra-cellular stresses. It is characterized by the formation of specialized double-membrane vesicles, autophagosomes, which engulf organelles and long-lived proteins, and in turn fuse with lysosomes for degradation and recycling. How autophagosomes emerge is still unclear. The Atg1 kinase plays a crucial role in the induction of autophagosome formation. While several… CONTINUE READING


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