Unraveling the function of Arabidopsis thaliana OS9 in the endoplasmic reticulum-associated degradation of glycoproteins

@inproceedings{Httner2012UnravelingTF,
  title={Unraveling the function of Arabidopsis thaliana OS9 in the endoplasmic reticulum-associated degradation of glycoproteins},
  author={Silvia H{\"u}ttner and Christiane Veit and Jennifer Schoberer and Josephine Grass and Richard Strasser},
  booktitle={Plant Molecular Biology},
  year={2012}
}
In the endoplasmic reticulum, immature polypeptides coincide with terminally misfolded proteins. Consequently, cells need a well-balanced quality control system, which decides about the fate of individual proteins and maintains protein homeostasis. Misfolded and unassembled proteins are sent for destruction via the endoplasmic reticulum-associated degradation (ERAD) machinery to prevent the accumulation of potentially toxic protein aggregates. Here, we report the identification of Arabidopsis… CONTINUE READING
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