Unraveling the Proteomic Profile of HER2: Searching for Putative Biomarkers in Plasma from Breast Cancer Patients by High-Resolution Label-Free MSE Proteomics

@inproceedings{Panis2012UnravelingTP,
  title={Unraveling the Proteomic Profile of HER2: Searching for Putative Biomarkers in Plasma from Breast Cancer Patients by High-Resolution Label-Free MSE Proteomics},
  author={Carolina Panis and A. C. S. A. Herrera and Eliana Abdelhay},
  year={2012}
}
INTRODUCTION: Overexpression of the human epithelial growth factor receptor 2 (HER2) is a frequent event in breast tumors correlated with tumor aggressiveness and poor patient prognosis. The proteomic identification of circulating markers in breast cancer is a current challenge, especially due to the inexistence of biomarkers related to disease prognosis. METHODS: In this study, we determined the proteomic profile in plasma of breast cancer patients presenting positive (n=28) and negative (n=31… CONTINUE READING