Unraveling stress-induced toxicity properties of graphene oxide and the underlying mechanism.

Abstract

Graphene oxide shows stress-induced toxicity properties in vivo under different pathophysiological conditions. A dual-path chemical mechanism, involving the overproduction of hydroxyl radicals and the formation of oxidizing cytochrome c intermediates, is responsible for the toxicity properties. 
DOI: 10.1002/adma.201202678

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