Unraveling Macrophage Heterogeneity in Erythroblastic Islands


Mammalian erythropoiesis occurs within erythroblastic islands (EBIs), niches where maturing erythroblasts interact closely with a central macrophage. While it is generally accepted that EBI macrophages play an important role in erythropoiesis, thorough investigation of the mechanisms by which they support erythropoiesis is limited largely by inability to… (More)
DOI: 10.3389/fimmu.2017.01140