Unproven methods of cancer management: Laetrile

  title={Unproven methods of cancer management: Laetrile},
  journal={CA: A Cancer Journal for Clinicians},
  • Published 1991
  • Medicine
  • CA: A Cancer Journal for Clinicians
“Laetrile” is used interchangeably with “amygdalin” to designate naturalsubstances, derived primarily from apricots and almonds, that can releasecyanide, which is lethal to living organisms. In the 1920s, Dr. Ernst T. Krebs, Sr., formulated a theory that amygdalin could kill cancer cells. Histheory was inconsistent with biochemical facts and has since been modifiedat least twice by his son, Ernst T. Krebs, Jr. Extensive work has been doneby cancer scientists to test the claim that Laetrile… Expand
12 Citations
Enzymes, Trophoblasts, and Cancer: The Afterlife of an Idea (1924-2008)
  • R. Moss
  • Medicine
  • Integrative cancer therapies
  • 2008
In central Europe, India, and other parts of the globe, the use of pancreatic enzymes as an adjuvant treatment for cancer has become a fairly routine practice, at least among those doctors who utilize complementary and alternative medicine (CAM). Expand
Life-Threatening Interaction Between Complementary Medicines: Cyanide Toxicity Following Ingestion of Amygdalin and Vitamin C
This case highlights the fact that CAMs can produce life-threatening toxicity, and adds a further note of caution, namely, the potential for serious interactions between CAMs, particularly where there is no tradition of concomitant use. Expand
Advanced research on anti-tumor effects of amygdalin.
Amygdalin is a natural product that owns antitumor activity, less side effects, widely sourced and relatively low priced, which make the amygdalin a promising antitUMor drugs, if combined with conditional chemotherapy drugs, which can produce synergistic effect. Expand
Co-administration of amygdalin and deoxynivalenol disrupted regulatory proteins linked to proliferation of porcine ovarian cells in vitro
Results of this in vitro study indicate that co-exposure of amygdalin and deoxynivalenol may act to stimulate proliferation-associated peptides in porcine ovarian granulosa cells, and thus alter cell proliferation and normal follicular development. Expand
Hydroxocobalamin (vit b12a) effectively reduced extent of cyanide poisoning arising from oral amygdalin ingestion in rats
This study investigated the efficacy of hydroxocobalamin in reducing cyanide toxicity arising from amygdalin administration in rats. Amygdalin at its therapeutic dose (20 mg/kg body weight) wasExpand
Sensitive Monitoring of Amygdalin and 5-Hydroxytryptamine in Food Supplements Using HILIC OH5 Chromatography
Amygdalin is a cyanogenic glycoside found in pits and kernels of numerous plants especially from the family Rosaceae. Recently, in some countries, food supplements containing amygdalin have beenExpand
Potential Physician Malpractice Liability Associated with Complementary and Integrative Medical Therapies
Legal rules relevant to potential malpractice liability for complementary and integrative care, a framework in which physicians can assess liability risk, and specific strategies for liability management are proposed are proposed. Expand
Amygdalin: Toxicity, Anticancer Activity and Analytical Procedures for Its Determination in Plant Seeds
The aim of this review is to present the current state of knowledge on the sources, toxicity and anticancer properties of amygdalin, and analytical methods for its determination in plant seeds. Expand
Toxic Phytochemicals and Their Potential Risks for Human Cancer
Many natural compounds found in several commonly consumed plants are potential carcinogens or tumor promoters and should be avoided. Expand
Evidence Supporting Product Standards for Carcinogens in Smokeless Tobacco Products
Levels of TSNA in smokeless tobacco products played a significant role in carcinogen exposure levels and are necessary to decrease exposure to these toxicants and potentially to reduce risk for cancer. Expand