Unproven methods of cancer management: Laetrile

@article{1991UnprovenMO,
  title={Unproven methods of cancer management: Laetrile},
  author={},
  journal={CA: A Cancer Journal for Clinicians},
  year={1991},
  volume={41}
}
  • Published 1991
  • Medicine
  • CA: A Cancer Journal for Clinicians
“Laetrile” is used interchangeably with “amygdalin” to designate naturalsubstances, derived primarily from apricots and almonds, that can releasecyanide, which is lethal to living organisms. In the 1920s, Dr. Ernst T. Krebs, Sr., formulated a theory that amygdalin could kill cancer cells. Histheory was inconsistent with biochemical facts and has since been modifiedat least twice by his son, Ernst T. Krebs, Jr. Extensive work has been doneby cancer scientists to test the claim that Laetrile… 
14 Citations

Life-Threatening Interaction Between Complementary Medicines: Cyanide Toxicity Following Ingestion of Amygdalin and Vitamin C

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Co-administration of amygdalin and deoxynivalenol disrupted regulatory proteins linked to proliferation of porcine ovarian cells in vitro

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Results of this in vitro study indicate that co-exposure of amygdalin and deoxynivalenol may act to stimulate proliferation-associated peptides in porcine ovarian granulosa cells, and thus alter cell proliferation and normal follicular development.

Hydroxocobalamin (vit b12a) effectively reduced extent of cyanide poisoning arising from oral amygdalin ingestion in rats

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It is concluded that rats can be protected from the deleterious effects of cyanide poisoning due to amygdalin ingestion by the concomitant administration of hydroxocobalamin.

Sensitive Monitoring of Amygdalin and 5-Hydroxytryptamine in Food Supplements Using HILIC OH5 Chromatography

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A fast hydrophilic interaction liquid Chromatography-high performance liquid chromatography (HILIC-HPLC) method was developed and applied to the determination of amygdalin and serotonin in capsules containing apricot kernels and sea buckthorn berries as well as toThe determination of Amygdalin in apricOT kernels and serotonin as a minority compound in sea buckstorn samples for food supplements.

Effect of amygdalin on MCF-7, MDA-MB-231 and T-47D breast cancer cells in the in vitro study

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Amygdalin anti-cancer activity may be selective in relation to different cell types, and examined breast cancer cells are more sensitive to amygdalin than normal cells.

Potential Physician Malpractice Liability Associated with Complementary and Integrative Medical Therapies

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Legal rules relevant to potential malpractice liability for complementary and integrative care, a framework in which physicians can assess liability risk, and specific strategies for liability management are proposed are proposed.

Amygdalin: Toxicity, Anticancer Activity and Analytical Procedures for Its Determination in Plant Seeds

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The aim of this review is to present the current state of knowledge on the sources, toxicity and anticancer properties of amygdalin, and analytical methods for its determination in plant seeds.

Toxic Phytochemicals and Their Potential Risks for Human Cancer

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Many natural compounds found in several commonly consumed plants are potential carcinogens or tumor promoters and should be avoided.

Evidence Supporting Product Standards for Carcinogens in Smokeless Tobacco Products

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Levels of TSNA in smokeless tobacco products played a significant role in carcinogen exposure levels and are necessary to decrease exposure to these toxicants and potentially to reduce risk for cancer.

Medical information on the Internet: a study of an electronic bulletin board.

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The findings suggest that medical information available on Internet discussion groups may come from nonprofessionals and may be unconventional, based on limited evidence, and/or inappropriate.